05 Jan, 2016
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Worksheets on Current Topics for Banking English Test Papers.
Nirdeshak is developing tailor made comprehension section from the recent news articles published in leading newspapers across the world. It is important to recognizing letters and words in the passage, as it is the first step in learning to read. For students it is vital that students comprehend, or understand, what they are reading. They must be able to get the meaning of the text: What is the author telling the reader?
…………………………………………………….Passage for Comprehension………..
Healthy or Sick
Rutgers scientists have uncovered biological pathways in the roundworm that provide insight into how tiny bubbles released by cells can have beneficial health effects, like promoting tissue repair, or may play a diabolical role and carry disease signals for cancer or neurodegenerative diseases like Alzheimer’s
In a new study, published in Current Biology, Rutgers scientists isolated and profiled these sub-micron sized cells, known as extracellular vesicles (EVs) in adult C. elegans and identified 335 genes that provide significant information about the biology of EVs and their relationship to human diseases.
They and colleagues from Princeton University, the University of Oxford and Albert Einstein College of Medicine, determined that 10 percent of the 335 identified genes in the roundworm regulate the formation, release, and possible function of the EVs. Understanding how EVs are made, dispersed and communicate with other cells can shed light on the difference between EVs carrying sickness or health.
“These EV’s are exciting but scary because we don’t know what the mechanisms are that decide what is packaged inside them.” said Maureen Barr, lead author and a professor in the Department of Genetics in Rutgers’ School of Arts and Sciences. “It’s like getting a letter in the mail and you don’t know whether it’s a letter saying that you won the lottery or a letter containing anthrax.”
For decades scientists believed that the EV material released by some human cells – which can only be seen through high-tech electron microscopes – was nothing more than biological debris.
While this theory has changed – with researchers now having a better understanding of the role these EVs play in cancer, infectious diseases and neurodegenerative disorders – scientists still aren’t certain how they are made or why the same parcels can result in different outcomes.
But Barr said using C. elegans, which have many genes similar to humans, Rutgers scientists have identified new pathways that could control the production of EVs and the cargo they carry, including the proteins responsible for polycystic kidney disease, the most commonly inherited disease in humans. The polycystic kidney disease gene products are secreted in tiny EVs from both humans and worms and no one knows why these proteins are in the EVs, she said.
“The knowledge gained from this tiny worm is essential for determining the biological significance of EVs, for understanding their relationship to human diseases like polycystic kidney disease, and for harnessing their potential therapeutic uses, “Barr said.
Because EVs are found in bodily fluids like urine, blood and cerebral spinal fluid, Barr said it is nearly impossible to determine the cellular source from which they are derived. This is why very little is known about how EVs are made and how the molecular cargo is released.
By understanding how a cell makes and packages proteins, lipids and nucleic acids into EVs, Barr said, pharmaceutical treatments and therapies could be developed, for instance, that would prevent cancer cells from producing EVs carrying cargo necessary for tumor growth.
“When we know exactly how they work, scientists will be able to use EVs for our advantage,” said Barr. “This means that pathological EVs that cause disease could be blocked and therapeutic EVs that can help heal can be designed to carry beneficial cargo.”
………………………………………….End of the Passage…………..
What is the correct meaning of the following words as used in the context of given passage.
a) to receive property by succession
b) to receive a title of honor
c) to get loan money
d) to receive by transmission of hereditary factors
a) secret of the nature unknown to man
b) to push away
c) substance discharged from cell
Source of this article: http://phys.org/news/2015-12-healthy-sick-tiny-cell.html
The Swedish newspaper was recently asked it to delete the reference made by President Pranab Mukherjee to the Bofors scam in an interview to it, as a claim protested by the Indian Government on 27 May 2015. India has expressed disappointment over the disrespect shown to the President, the newspaper has defended its right to publish what was said during the interview.
Know, who is Vijay Kelkar and what is PPP !
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Know, who is Yaduveer Krishnadatta Chamaraja Wadiyar !
Yaduveer Krishnadatta Chamaraja Wadiyar was crowned as the new Maharaja of of Mysuru (Mysore) royal family. He is the 23-year old grandson of Princess Gayathri Devi, who was the eldest daughter of the last Maharaja of Mysore, Sri Jayachamarajendra Wadiyar. The coronation was held at Mysuru’s famous Amba Vilas Palace, which was decked up for the occasion.
Know about Sepp Blatter!
Swpp Blatter, was re-elected as FIFA president for a fifth term at the 65th Annual Congress of FIFA held at Zurich for four year term.
Prince Ali bin al-Hussein of Jordan stood against Blatter in this election. It is worth mentioning that FIFA is going through a major controversy regarding corruption in the organisation with two FIFA vice presidents and a recently elected FIFA executive committee member still in custody.